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Northwestern University Feinberg School of Medicine
Northwestern University
Clinical and Translational Sciences Institute
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Events

Attend one of our events. View the calendar below to see what’s next on our schedule.

Oct

27

M-I Dept. Virtual Seminar - Why Does HCMV Encode A Glycoprotein H Complex That Lacks Glycoprotein L?

Online - 12:00 PM - 1:00 PM

Title: "Why Does HCMV Encode A Glycoprotein H Complex That Lacks Glycoprotein L?" Speaker: Jeremy Kamil, PhD / LSU Health, Shreveport Host: Richard Longnecker, PhD Topic: In many enveloped viruses, a single glycoprotein suffices to bind host receptors and fuse membranes to initiate infection.  Herpesviruses, however, encode a large number of glycoproteins, several of which play roles in immune evasion and never leave the endoplasmic reticulum, while other glycoproteins, comprised of or built upon glycoprotein H (gH)/ glycoprotein L (gL) heterodimers, bind receptors to regulate membrane fusion events which are catalyzed by glycoprotein B, the proximal fusogen for all herpesviruses.  Human cytomegalovirus (HCMV), the so called “prototype” betaherpesvirus, encodes at least three glycoprotein H complexes, one of which, gH/UL116, lacks the canonical gH dimerization partner, gL.  I will share results that suggest a function for this complex. Zoom Meeting Link: Join Zoom Meeting https://northwestern.zoom.us/j/91423489708?pwd=UVBOTDc3azJ6Z2QyWVYxY0RFUndyQT09 Meeting ID: 914 2348 9708 Passcode: 344234  

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Oct

29

The State of IPHAM

Online - 12:00 PM - 1:00 PM

Registration required. Hosted by the Institute for Public Health and Medicine (IPHAM) at Northwestern University. Presenter: Ronald T. Ackermann, MD, MPH Senior Associate Dean for Public Health Director, Institute for Public Health and Medicine (IPHAM) Director, Center for Diabetes and Metabolism Professor of Medicine and Medical Social Sciences and Medicine Northwestern University Feinberg School of Medicine For more public health news, events, and announcements, visit the IPHAM website: https://feinberg.northwestern.edu/ipham

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Nov

03

M-I Dept. Virtual Seminar - Forest Rohwer, PhD

Online - 12:00 PM - 1:00 PM

Seminar Title: TBA Speaker: Forest Rohwer, PhD, San Diego State University Host: Virology Graduate Students and Postdocs / Coordinator, Neil Kuehnle, Graduate Student Topic: TBA Zoom Meeting Link: TBA    

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Nov

03

MS Health Services and Outcomes Research Info Session

Online - 1:00 PM - 2:00 PM

Please join us for an information session about the Master's in Health Services and Outcomes Research Program. The HSOR program prepares health researchers for careers in academia, health systems, and research and policy organizations. The master’s curriculum emphasizes research methods (biostatistics, quantitative methods and study design, qualitative methods), manuscript writing and grant writing. The degree can be completed in two years, part-time. Attend an online information session to learn more: Tuesday, November 3, 2020 1:00pm – 2:00pm CT The information sessions will cover the master’s curriculum, the program’s certificate offerings, the hybrid format experience, and the application process. Prospective students are also encouraged to bring their questions.

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Nov

10

M-I Dept. Virtual Seminar - Sangjin Kim, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Sangjin Kim, PhD / University of Illinois Urbana-Champaign Host: Hank Seifert, PhD Topic: TBA Zoom: TBA  

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Nov

13

"Striatal GPCR-based Neuromodulation and its Behavioral Implications"

Online - 12:00 PM - 1:00 PM

The Department of Physiology welcomes Dr. Shana Augustin with NIH. Striatal neuromodulators have critical roles in motor control, decision-making and addiction. These neuromodulators exert their functions through G-protein-coupled receptors (GPCRs) on striatal neurons that activate second messenger intracellular cascades to affect neuronal signaling. Thus, understanding the cellular, subcellular, and synaptic mechanisms underlying neuromodulation is critical to advancing our knowledge of striatal function. I have taken a multifaceted approach to study striatal neuromodulation. The focus of my recent research has been the action of dopamine on different cellular populations of striatal dopamine D2 receptors in the induction of endocannabinoid (eCB)-dependent long-term depression (LTD), the downstream activation/inhibition of the cAMP-PKA signaling pathway, as well as the behavioral implications of this signaling. I identified a dual mechanism for D2R modulation of corticostriatal LTD induction at medium spiny neuron (MSN) synapses involving D2Rs on cholinergic interneurons and indirect pathway MSNs. In addition, I can simultaneously measure dopamine release and subsequent downstream GPCR mediated cAMP-PKA signaling in striatal brain slices using a genetically encoded fluorescent (GEF) cAMP sensor, cAMP Difference Detector in situ (cADDis), and Fast-Scan Cyclic Voltammetry. These experiments indicate that during afferent stimulation MSN-cAMP signaling is primarily influenced by dopamine transmission. Additionally, I have shown that D2 MSN-cAMP signaling is important for action initiation. Drugs of abuse can interfere with eCB-mediated synaptic plasticity in a synapse-specific, and possibly in an eCB type selective manner. I am using a GEF sensor that enables the optical recording of eCBs in real-time and in behaving animals, as well as eCB-specific conditional knockout animals to understand how the eCB system influences synapses and circuits to promote the pathophysiology of Alcohol Use Disorder. Using a multidisciplinary approach, these experiments have helped to further elucidate unique functions of GPCR neuromodulation within the basal ganglia circuitry and the functional relevance of these circuits.

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Nov

17

M-I Dept. Virtual Seminar - Feng Gu, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker : Feng Gu, PhD / Postdoctoral Scholar, Naghavi Lab Host: Mojgan Naghavi, PhD Topic: TBA Zoom: TBA

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Nov

24

M-I Dept. Virtual Seminar - Cooper Hayes

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Cooper Hayes, Graduate Student/ Longecker Lab Host: Richard Longnecker, PhD Topic: TBA Zoom: TBA  

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Dec

01

M-I Dept. Virtual Seminar - Melissa Brown, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Melissa Brown, PhD / Professor/ Northwestern University Host: Laimonis Laimins, PhD Topic: TBA Zoom: TBA

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Dec

08

M-I Dept. Virtual Seminar - Francesco Marangoni, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Francesco Marangoni, PhD / University of California, Irvine Host: Booki Min, DVM, PhD Topic: TBA Zoom: TBA

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Dec

15

M-I Dept. Virtual Seminar - Mee-Ngan Frances Yap, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Mee-Ngan Frances Yap, PhD / Northwestern University Host: Laimonis Laimins, PhD Topic: TBA Zoom: TBA

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Jan

05

M-I Dept. Virtual Seminar - John Galvin, MD, MPH

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: John Galvin, MD, MPH / Adjunct Assistant Professor of Microbiology-Immunology Host: Stephen D. Miller, PhD Topic: TBA Zoom: TBA

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Jan

12

M-I Dept. Virtual Seminar - Michael Metzger, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Michael Metzger, PhD / Pacific Northwest Research Institute Host: Mojgan Naghavi, PhD Topic: TBA Zoom: TBA

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Jan

15

Cellular Pathology in the Prefrontal Cortex in Neuropathic Pain

Online - 12:00 PM - 1:00 PM

Theodore Price, PhD Eugene McDermott Professor Director, Systems Neuroscience Program, School of Behavioral and Brain Sciences Director of the Center for Advanced Pain Studies University of Texas (UT) at Dallas Theodore (Ted) Price, PhD, is the Eugene McDermott Professor and Director of the Systems Neuroscience Program in the School of Behavioral and Brain Sciences at University of Texas (UT) at Dallas. He is also the Director of the Center for Advanced Pain Studies at UT Dallas. He did his PhD work with Chris Flores and Ken Hargreaves at UT Health San Antonio and a postdoctoral fellowship at McGill University with Fernando Cervero. He started his independent laboratory in 2007 at University of Arizona School of Medicine and moved to UT Dallas in 2014. His lab is interested in molecular mechanisms driving the transition to chronic pain with a focus on drug development for chronic pain disease modification and on peripheral and central mechanisms of neuronal plasticity in response to injury. He has won numerous awards including the John C Liebeskind Early Career Scholar Award from the American Pain Society and The Patrick D. Wall Young Investigator Award from the International Association for the Study of Pain. Ted serves on editorial boards for leading pain and neuroscience journals such as Pain and Journal of Neuroscience, and is a standing member of the Somatosensory and Pain Study Section for NIH.

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Jan

19

M-I Dept. Virtual Seminar - Evan A. Scott, PhD

Online - 12:00 PM - 1:00 PM

Title: TBA Speaker: Evan Scott, PhD / Northwestern University Host: Laimonis Laimins, PhD, Professor and Chair Topic: TBA Zoom Link: TBA  

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