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| Bioinformatics Core (BioGNU) |
| Biostatistics Core |
| Cell Imaging Facility |
| Flow Cytometry—Interdepartmental Immunobiology Center |
| Flow Cytometry—Robert H. Lurie Comprehensive Cancer Center of Northwestern University (RHLCCC) |
| Genomics Core Facility |
| Monoclonal Antibody Core |
NUgene Project |
| siRNA Library Core - High Throughput Analysis Laboratory |
Transgenic-Targeted Mutagenesis Facility |
| Behavioral Phenotyping Core Facility (FSM Core as of FY08) |
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| Please click here for a complete listing of Northwestern University's Shared and Core Facilities |
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Bioinformatics Core (BioGNU)  |
| Biomedical informatics expertise and services that broadly encompass the design, development, and operation of web-based data access, data handling services, data integration services and data analysis services for life science data |
| Services Provided: Bioinformatics systems development and consulting; Bioinformatics software-vector NTI site license; Matlab site license; Direct project support for phenotype/genotype studies |
| Director: Warren Kibbe, PhD |
| Location: 676 N Saint Clair, 12th floor, Chicago Campus |
| Web Site: http://www.cancer.northwestern.edu/Research/core_facilities_info.cfm?ID=1 |
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| Biostatistics Core |
| Biostatistical support and expert consultation for the planning, design, development and execution of studies, and the analysis and interpretation of data, as well as the preparation of reports and manuscripts for basic science, clinical and epidemiologic research projects |
| Services Provided: Development of new studies, statistical analyses, data management and education |
| Director: Jenny Huang, PhD |
| Location: 680 N. Lake Shore Drive, 11th floor, Chicago Campus |
| Web Site: http://www.cancer.northwestern.edu/Research/core_facilities_info.cfm?ID=2%20 |
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| Cell Imaging Facility |
| Studies biological processes at the tissue, cellular, and subcellular levels |
| Services Provided: Light microscopy, electron microscopy, and image processing/analysis |
| Director: Teng-Leong Chew, MD |
| Location: 303 E. Chicago Avenue, Morton & Searle Buildings, 2nd Floor, Chicago Campus |
| Web Site: http://www.feinberg.northwestern.edu/cif/ |
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| Flow Cytometry—Interdepartmental Immunobiology Center |
| Access to "user friendly" instrumentation for strictly analytical flow cytometry applications |
| Services Provided: Routine data collection/analysis consultation for experiment design and sample preparation; cell sorting and assay development, user access to Becton Dickinson flow machines; training for usage of machines is provided as a prerequisite for use of the facility. |
| Director: Stephen Miller, PhD |
| Location: 300 E. Superior, Tarry Building, 6th Floor, Chicago Campus |
| Web Site: http://www.medschool.northwestern.edu/depts/ibc/core.html |
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| Flow Cytometry—Robert H. Lurie Comprehensive Cancer Center of Northwestern University (RHLCCC) |
| Comprehensive flow cytometry and cell sorting services |
| Services Provided: Routine data collection/analysis consultation for experiment design and sample preparation; cell sorting and assay development, user access to Becton Dickinson flow machines; training for usage of machines is provided as a prerequisite for use of the facility. |
| Director: Charles Goolsby, PhD |
| Location: 710 North Fairbanks Court, 8th Floor, Chicago Campus |
| Web Site: http://www.cancer.northwestern.edu/Research/core_facilities_info.cfm?ID=7 |
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| Genomics Core Facility |
| Gene expression profiling, SNP analysis, DNA extraction and DNA sequencing |
| Services Provided: High Through put DNA extraction; SNP Analysis; Whole Genome Amplification; Expression profiling services; Globin mRNA ; reduction from blood total RNA; RNA quality control; RT-PCR; Sequencing; Educational Activities; Instrument usage |
| Director: Nadereh Jafari, PhD |
| Location: 300 E. Chicago Avenue, Ward Building, 9th Floor, Chicago Campus |
| Web Site: http://www.medschool.northwestern.edu/cgm/genomics/index.html/ |
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| Monoclonal Antibody Core |
| Creation of hybridoma cell lines & production of monoclonal antibodies from these cell lines |
| Services Provided: Immunization of animals with antigens or direct injection of cDNAs, test bleeds, evaluation of immune response, somatic cell fusions, screening and cloning of hybridomas, antibody isotyping and mycroplasma testing, large scale antibody production |
| Director: Izolda Popova, MD, PhD |
| Location: 300 E. Chicago Avenue, Ward Building, 19th Floor, Chicago Campus |
| Web Site: http://www.basic.northwestern.edu/sharedresources/monoclonal/ |
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| NUgene Project |
NUgene is a biospecimen repository with longitudinal medical information from participating patients at Northwestern-affiliated outpatient clinics and hospitals. Participants' consent to genetic research on their DNA samples and health data. NUgene is an institutional resource providing investigators with coded DNA samples and data for genomics research, as well as a vehicle for participant recruitment and contact for secondary studies. |
Services Provided: Coded DNA samples and questionnaire/health data; co-recruitment of research subjects to bank participant DNA; grant application support; IRB application consultation; participant contact for secondary studies; and study consultation |
Director: Wendy Wolf, PhD |
Location: 676 N. Saint Clair, Suite 1260, Chicago Campus |
Web Site: http://www.nugene.org/ |
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| siRNA Library Core - High Throughput Analysis Laboratory |
| The HTA provides academic, industrial, and private researchers with equipment and expertise for the development and execution of high throughput biological analysis and screening. The facility is fully equipped with state-of-the-art liquid handling, plate detection and automated microbial culture handling capabilities. |
| Services Provided: Automated colony picking, Yeast two-hybrid analysis, Synthetic Genetic Array (SGA) analysis, Microbial library replication and rearraying, Enzyme and cell-based assays, Hit picking and library reformatting, HT solid phase extraction, Large-scale pipetting/plate filling |
| The facility also assists researchers in developing HT nucleic acid purification and cloning protocols and develops novel automated methods to increase assay and sample preparation throughput. Please browse this site for a complete description of facility capabilities, and feel free to contact HTA to discuss your project. |
| Location: 2205 Tech Drive, Hogan Building, 2nd Floor, Evanston Campus |
| Web Site: http://www.biochem.northwestern.edu/hta/about.htm |
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Transgenic-Targeted Mutagenesis Facility |
| Produce knockout chimeric mice using homologous recombination and mouse embryonic stem cells |
| Movie 1 |
| Movie 2 |
| Services Provided: |
| Director: Warren Tourtellotte, PhD, Lynn Doglio, PhD |
| Location: 300 E. Superior, Tarry Building, 4th Floor |
| Web Site: http://www.lurie.northwestern.edu/Research/core_facilities_info.cfm?ID=17 |
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| Behavioral Phenotyping Core Facility (FSM Core as of FY08) |
| Services Provided: TBD |
| Director: John Disterhoft, PhD |
| Location: TBD |
| Web Site: TBD |
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